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There is accumulating evidence also for iatrogenic AD

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    There is accumulating evidence also for iatrogenic AD


    MONDAY, SEPTEMBER 11, 2023


    Professor John Collinge on tackling prion diseases

    “The best-known human prion disease is sporadic Creutzfeldt-Jakob disease (sCJD), a rapidly progressive dementia which accounts for around 1 in 5000 deaths worldwide.”

    There is accumulating evidence also for iatrogenic AD. Understanding prion biology, and in particular how propagation of prions leads to neurodegeneration, is therefore of central research importance in medicine.


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    #2
    flatfish, I am way out of my depth here but I looked at the article in your first link and wondered what this paragraph meant:

    Our discovery of human transmission of amyloid-beta pathology, mentioned above, in individuals treated many years earlier in childhood with human cadaver-derived pituitary growth hormone (c-hGH) accidentally contaminated with amyloid-beta seeds (prions) has wide implications for understanding, preventing and treating neurodegenerative diseases.
    Is this what is meant about iatrogenic AD? Do you happen to know why individuals were treated in childhood with "human cadaver-derived pituitary growth hormone (c-hGH) accidentally contaminated with amyloid-beta seeds (prions)"? Were these children who weren't growing normally?
    SPMS diagnosed 1980. Avonex 2001-2004. Copaxone 2006-2009. Glatopa (glatiramer acetate = Copaxone) since December 2020.

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