I wasn't sure where to post this. I'm thinking of a hypothetical treatment for obesity that alters certain parts of the digestive system. As with all therapy, this is not without drawbacks.
Here is how the digestive system would be modified:
1. No carbohydrate of any type would be absorbed into the bloodstream -- even monosaccharides would be excreted in the stool via the colon
2. No carbohydrate of any type would be digested -- starches would no longer convert to sugars. Enzymes that digest carbohydrate [such as amylase] are absent.
3. No part of the digestive system produces substances with a pH below 7. This means bile acids would be absent and the stomach no longer produces HCl.
4. No lipids of any kind are absorbed into the villi or microvilli [even if completely digested]
5. No lipids of any kind are digested [lipases are absent]
6. No greasy substance [even if not classified as a lipid] will be absorbed into the villi/microvilli or digested
7. No part of the digestive system will produce emulsifiers
8. Sodium chloride molecules are not absorbed into the bloodstream
9. Neither sodium nor chloride ions or elements are absorbed into the bloodstream
10. No molecule containing any form of chlorine or sodium ever gets absorbed into the bloodstream
11. Toxic alcohols [such as ethanol] are not absorbed into the bloodstream
12. Vomiting never occurs under any condition
13. To prevent cramps and bloating, all residual water-soluble molecules [including water-soluble intestinal gases BUT excluding aforementioned substances that are not to be absorbed] are absorbed into the bloodstream. This also prevents flatulence, burping, and belching.
14. To prevent diarrhea, most of the water in the stool is absorbed into the bloodstream until there is just enough water in the stool to keep the gut flora healthy. Assuming the diet is high in fat, constipation will not occur no matter how low the stool's water content is. Steatorrhea will prevent constipation.
15. To prevent diverticulitis, the intestinal muscles completely relax during the relaxation phase of peristalsis. When they un-relax they do so in a clonic manner such that they don't strain. These smooth-muscles never contract in a tonic manner as that contributes to diverticulitis and spastic colon. These muscles also un-relax with low-enough intensity that they don't overwork themselves.
16. Caffeine is not absorbed from the digestive system. This means one can enjoy the taste and smell of coffee without the jitters.
After the above alterations take place, the formerly-obese patient can eat all the pleasurable high-fat, high-carb, and high-salt foods desired and still lose weight. Right?
What would be the medical disadvantages of this cure for obesity?