Explorations Program IV

Created Aug. 2013 Page 1 of 9

Rev. Aug 2015

Description The Explorations Program IV is intended to allow qualified investigators to seek funding for research directly related to prion diseases and human neurodegenerative diseases and dementias where the etiology involves protein misfolding and the pathogenesis has prion-like characteristics. Funding is accessible for all relevant fields of inquiry in the themes as described below. The deadline for submission of applications is November 30, 2015. Grantees will be expected to participate in the training of young investigators, especially graduate students and fellows, and their stipends may be paid from Alberta Prion Research Institute (Prion Institute) grants. Trainees may hold other awards or salary support while receiving stipends from Prion Institute grants. All usual operating expenses for a research project that are consistent with the Tri-Council policy on the use of grant funding (www.nserc.ca) will be allowable for grants funded in an Explorations Competition IV except salaries for investigators and overhead costs. Final decisions on the amount of funding awarded and limitations on specific categories of spending remain with the Prion Institute and will be identified in an Alberta Innovates Bio Solutions award agreement. Maximum amounts available for funding: There are two tiers of funding available in the Explorations Competition IV: Tier I: Grants of up to $200,000 for a maximum period of two years Tier II: Grants of up to $500,000 for a maximum period of three years Themes accessible for funding: Prion Diseases

Protein Folding and Misfolding

Pathobiology of Transmissible Spongiform Encephalopathies (TSEs)

Surveillance and Control

TSEs and Society Prion-like human neurodegenerative diseases and dementias

Protein Folding and Misfolding Prion-like Mechanisms in Pathobiology

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