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  1. Deferred use of Avastin not associated with diminished efficacy

    Deferred use of bevacizumab for recurrent glioblastoma is not associated with diminished efficacy

    David E. Piccioni, Julia Selfridge, Reema R. Mody, Reshmi Chowdhury, Sichen Li, Shadi Lalezari,...
  2. Cancer cells get energy and raw materials for growth from glucose

    Ludwig researchers have elucidated a key mechanism by which cancer cells change how they metabolize glucose to generate the energy and raw materials required to sustain runaway growth.

    Published...
  3. A potential new treatment option for patients with brain cancer

    A novel drug for patients with brain cancer, 2B3-101, has shown preliminary positive results. The Dutch biotech to-BBB has developed Glutathione PEGylated liposomal doxorubicin (2B3-101) and...
  4. Frontline Avastin Fails to Boost Glioblastoma Survival in Key Trials

    Adding bevacizumab to frontline radiation and temozolomide therapy for glioblastoma produced disappointing results in a double-blind, placebo-controlled phase III trial.

    Bevacizumab (Avastin)...
  5. As for the quality-of-life and symptom end points...

    As for the quality-of-life and symptom end points of the RTOG 0825 trial, Dr. Tsien said she agrees that the effects of Avastin in reducing vascular permeability and edema might lead to a "pseudo...
  6. No Benefit to Avastin for Newly Diagnosed Glioblastoma?

    A heated debate has again developed over the use of Avastin for the treatment of glioblastoma, this time in the front-line setting in combination with chemotherapy in newly diagnosed patients.
    ...
  7. No Benefit Offered By Avastin For Newly Diagnosed Glioblastoma

    The angiogenesis inhibitor bevacizumab (Avastin) failed to increase overall survival (OS) or statistically significant progression-free survival (PFS) for glioblastoma patients in the frontline...
  8. Avastin fails to prolong life in glioblastoma brain cancer patients

    [Wow! This is blockbuster news! In one study, patients who were expected to benefit the most from Avastin based on "genetic" testing had the worst survival rates.]

    (AP) - New research raises fresh...
  9. Avastin (bevacizumab) and Sprycel (dasatinib) shows promise in Glioblastomas

    The drug bevacizumab, also known by the trade name Avastin, shrinks tumors briefly in patients with an aggressive brain cancer known as glioblastoma multiforme, but then they often grow again and...
  10. Smaller Radiation Fields Can Spare Brain When Treating GBM

    New research from Wake Forest Baptist Medical Center shows that patients suffering from aggressive brain tumors can be effectively treated with smaller radiation fields to spare the rest of the brain...
  11. Understanding Glioblastoma

    John de Groot, M.D.
    MD Anderson Cancer Center

    Gliomas. These primary brain tumors arise within the brain, but we don't know the cell of origin.

    There are multiple grades of gliomas -- grade...
  12. Treatment Options for Glioblastoma and other Gliomas

    Lawrence Recht, M.D.
    Director of Adult Neuro-Oncology
    Stanford Cancer Institute

    The foundation for glioblastoma treatment includes surgery, radiation and the chemotherapeutic agent,...
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