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Old 10-26-2006, 09:41 PM
SteveSS SteveSS is offline
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Join Date: Oct 2006
Posts: 1
Default Drug Interaction Questions

Hi. I'm a newbie. Sorta. I've been reading posts for about 6mo. Haven't really found much to help yet. This PN is driving me nuts. Good days, bad days, etc, etc. I wish I know what I did wrong to make my nerves start dying. I wish I could make it stop from progressing. I wish I knew what was going to happen next.
Anyway I finally have a question. (Doctors don't seem to know much)
I searched but didn't find anything.
Is there a list of drugs which can be detrimental? I know about statins, but are there others? Like Avodart or Flomax or BP meds.
How about flu shots. Will that trigger something?
Oh oh, been sitting too long. Here it comes. Gotta go for a walk.
Bye. SteveS
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Old 10-26-2006, 11:33 PM
Silverlady Silverlady is offline
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Join Date: Oct 2006
Location: Texas
Posts: 87
Default Several places to look

Some of the others will be checking in later. Most of us stay at Braintalk2 which is here: But we do check in here to see if there is someone who needs help.

There isn't a list as far as I know but there are lists of Medications and you can search that list for any medications you are interested in and read the
SIDE EFFECTS of that medication. You want to watch for peripheral Neuropathy there as well as some other terms. I'm hoping some one will come along and tell you what those terms are.

Here is one of the sites I use for medication:

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Old 10-27-2006, 12:43 AM
joy joy is offline
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Posts: 3,677

Hi Steve and welcome. Sorry you need to be here but you are among a good group of people here. Silverlady was right in using the computer to search everything you can about medications. I myself hate for anyone to have to be on statins but my husband is one because the alternative for him could be worse than having peripheral neuropathy. My doctor strongly suggests that I get a flu shot each year. In fact the year there was a shortage I was one of the few that did get one from his office. I myself have never felt that it made my pn worse.

Stick around and get to know us and keep asking questions.

Last edited by joy; 10-27-2006 at 12:49 AM. Reason: took out tacky
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Old 10-27-2006, 11:06 AM
jjano jjano is offline
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Posts: 108

While tons of folks are on "STATINS" , be sure your husband and any of your friends closely monitor how they feel while on ANY Cholesterol drug. While many people have irrritating leg , body and trunk pain, which can come and go, one can get a terrible case of ""Rhabdomyolysis"". In Nanc's case it struck one week-end. It was like coming down with the flu, but with no barfs or trotts. We stopped the meds and by Tuesday, all the damage was done. She had lost 95% of her strength and it has NEVER returned. That was over two years ago. So now the walk from her livingroom chair to the bathroom is the activity of the day and that also often requires help getting out of the chair.

We all react differently to med, but as you can see, "Rabdo" can make you an invalid almost over night, and there goes your life, dreams, and all of your basic abilities.


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Old 10-27-2006, 03:47 PM
JLW JLW is offline
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Join Date: Oct 2006
Posts: 67

Hi, Steve. I"m fairly new at this stuff as well.

But don't be misled. Yes, there is a Braintalk2 forum. Yes, there are PN'ers who post there.

But BrainTalk2 is NOT affiliated with this BrainTalk forum. Only some of the members go to both. It is not run with or legally connected with the original here.

I'm not saying BT2 is bad, I just wanted to let you know. Many people are misled by the name similarities and just assume it is a branch of this Original BrainTalk community.

(Personally, I prefer the original one here.)

I also wonder about drug interactions sometimes myself with things. I have a really good relationship with my pharmacist, so I usually check with him on everything even if I find stuff on the internet.

Welcome aboard the "PN Train".......... but sorry to see you have to be along for the ride.
'00 Auto accident, C6-7 bulge. '04 hypothyroid. '05 Rt foot neuroma surgery. '06 L5-S1 bulge, facet degen L4-5/L5-S1. '06 bilateral carpal tunnel. '07 Rt foot surgery-plantar fasciitis, heel spur, bunion, dislocated 2nd toe - resulted in RSD/CRPS. Rt&Lft carpal tunnel surgery Spring 2011.
Forum member since 2000
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Old 10-28-2006, 12:23 PM
nide44 nide44 is offline
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Join Date: Oct 2006
Location: Chesapeake Bay
Posts: 276

BT2 was developed when this site was down for a long while,
as an alternative site in the interim.
It is now called Neuro Talk and is used by many PN'ers.
It is not associated with 'hastypastry' in any way.
Politics and controversy are currently a lively topic at both.

Back to PN.
I stay away from statins. For cholesterol control, I've been using Zetia
(non-statin) for over 3 yrs.
I also stay away from artificial sweeteners of any type in any 'diet' foods or drinks. No 'Splenda' or saccharin or 'Sweet & Low' in my coffee.
They all make my feet hurt - BADLY !
Oh, BTW - no alcohol (or at least in very moderate portions).
That's what was a contributting factor to start my PN, 7 yrs ago.
Bob B
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Old 10-28-2006, 12:45 PM
mrsdoubtfyre mrsdoubtfyre is offline
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Location: Great Lakes
Posts: 944
Lightbulb many drugs deplete nutrients...

Besides statins--which damage tissue directly.

The most common is the diuretic family.
Diuretics are now first line choices for blood pressure.
They deplete thiamine (B1), potassium and magnesium.

Thiamine has always been a TREATMENT for PN..and it unlike drugs we have today actually helps to heal. There is no reason not to try it. It is inexpensive, no side effects, and readily available. Start at 200mg a day and work up to 500mg if necessary.

Low magnesium levels lead to muscle cramps, heart beat irregularities, increased pain, and poor sleep.

If one HAS to be on statins, then a quality CoQ-10 supplement may help prevent some of the terrible side effects. Statins suppress the body's enzymes that normally make CoQ-10... which is a critical nutrient for the mitochondrial functions (in every cell of the body) and esp. the HEART which has the greatest need for it.
information above for CoQ-10 and Thiamine.
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Old 10-30-2006, 07:35 PM
rose rose is offline
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Join Date: Oct 2006
Location: Northern California
Posts: 338
Default My aunt has been put on Norvast for high blood pressure

Oops. I spelled it wrong before. No wonder I couldn't find it.

Any reason a calcium channel blocker might be better for some? Or is that just the last drug being pushed by the pharm rep? We've eliminated everything else he tried to give her, so he's probably dreading this week's visit already.

By the way, my aunt probably weighs 100 lb soaking wet and is 83 years old. Dose?


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Old 10-31-2006, 12:38 AM
jjano jjano is offline
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Posts: 108

Hi Rose,
I don't know you aunts situation, but I can tell you my wife was on Norvasc**5mg and suffered 130 Angina attacks in Sept. of 05. The Dr raised the dosage to 10mg and the Angina attacks disappeared. For her at least, it worked miracles and for once , she had no side effects.

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Old 10-31-2006, 02:07 PM
mrsdoubtfyre mrsdoubtfyre is offline
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Location: Great Lakes
Posts: 944
Post Norvasc

Is a calcium channel antagonist. It dilates blood vessels.
It is not a new drug, as a matter of fact it is going off patent in a year or
so depending on how vigorous Pfizer fights the change.

It can cause dependent edema (of the legs) in some people. (that happened to
me-- so I use Cardizem CD now instead).

It is commonly used in the elderly. But attention needs to be paid to dosing.
Some elderly cannot handle high doses, as it may cause orthostatic
hypotension when standing suddenly.

Calcium channel blockers are not recommeded for people with heart failure.
Taking high doses of calcium for osteoporosis may lower the BP effects of Norvasc. However, some people get leg cramps from calcium channel blockers, and calcium is usually a remedy for that. It is only extremes in dosing that
should be monitored.
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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