BrainTalk Communities 10/2006-8/2011 Archives  

Go Back   BrainTalk Communities 10/2006-8/2011 Archives > Specific Neurological Conditions (M - Z) > Multiple Sclerosis

Reply
 
Thread Tools Display Modes
  #1  
Old 10-23-2006, 11:51 PM
AmyGrace AmyGrace is offline
New Community Member
 
Join Date: Oct 2006
Posts: 10
Default "Virus May Diminish Memory Decades Later" article

I think this article is interesting so I posted it in case others are interested, too. ~Amy Grace

Virus May Diminish Memory Decades Later


WASHINGTON (Oct. 23) - Forget where you left your glasses? Did those keys go missing again? Now you do not have to blame your spouse -- a virus may be to blame.

Scientists infected mice with the Theiler's murine encephalomyelitis virus -- which is similar to the human polio virus, shown above seven million times its actual size -- to study how it affected their memories.

A family of viruses that cause a range of ills from the common cold to polio may be able to infect the brain and cause steady damage, a team at the Mayo Clinic in Minnesota reported on Monday.

"Our study suggests that virus-induced memory loss could accumulate over the lifetime of an individual and eventually lead to clinical cognitive memory deficits," said Charles Howe, who reported the findings in the journal Neurobiology of Disease.

The viruses are called picornaviruses and infect more than 1 billion people worldwide each year. They include the virus that causes polio, as well as colds and diarrhea. People contract two or three such infections a year on average.

"We think picornavirus family members cross into the brain and cause a variety of brain injuries. For example, the polio virus can cause paralysis," Howe said.

"It can injure the spinal cord and different parts of the brain responsible for motor function. In the murine (mouse) virus we studied, it did the same thing and also injured parts of the brain responsible for memory."

The Mayo Clinic infected mice with a virus called Theiler's murine encephalomyelitis virus, which is similar to human poliovirus.

Infected mice later had difficulty learning to navigate a maze. Some were barely affected, while others were completely unable to manage, and when the mice were killed and their brains examined, a correlating amount of damage was seen in the hippocampus region, related to learning and memory.

One virus particularly likely to cause brain damage is enterovirus 71, which is common in Asia, the researchers said. It can cross over into the brain and cause encephalitis, a brain inflammation that can lead to coma and death.

"Our findings suggest that picornavirus infections throughout the lifetime of an individual may chip away at the cognitive reserve, increasing the likelihood of detectable cognitive impairment as the individual ages," the researchers wrote in their report.

"We hypothesize that mild memory and cognitive impairments of unknown etiology may, in fact, be due to accumulative loss of hippocampus function caused by repeated infection with common and widespread neurovirulent picornaviruses."

Other viruses are known to kill brain cells, including the herpes virus and human immunodeficiency virus or HIV.

http://articles.news.aol.com/news/_a...90009?cid=2194


10/23/06 12:09 ET


Copyright 2006 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. All active hyperlinks have been inserted by AOL.
Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
FYI - Article "Is suicidal behavior a condition is its own right?" Lara Survivors of Suicide 16 01-26-2008 09:44 AM
FYI - News article "Australia drought sparks suicides" Lara Survivors of Suicide 0 10-19-2006 04:38 PM
New improved "Copaxone" beginning clinical trials in MS xo++ Multiple Sclerosis 7 10-17-2006 05:46 PM
Asperger's Syndrome - "Aspie" - Attwood and Gray Lara Autism 7 10-13-2006 09:34 AM


All times are GMT -4. The time now is 05:08 PM.


Powered by vBulletin® Version 3.8.5
Copyright ©2000 - 2020, Jelsoft Enterprises Ltd.
BrainTalk Communities Incorporated